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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EOMES
All Species:
29.39
Human Site:
Y350
Identified Species:
53.89
UniProt:
O95936
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95936
NP_005433.2
686
72732
Y350
N
M
Q
G
N
K
M
Y
V
H
P
E
S
P
N
Chimpanzee
Pan troglodytes
XP_001165803
690
73333
Y354
N
M
Q
G
N
K
M
Y
V
H
P
E
S
P
N
Rhesus Macaque
Macaca mulatta
XP_001093085
737
80029
Y382
N
M
Q
G
N
K
M
Y
V
H
P
E
S
P
N
Dog
Lupus familis
XP_850738
688
72729
Y352
N
M
Q
G
N
K
M
Y
V
H
P
E
S
P
N
Cat
Felis silvestris
Mouse
Mus musculus
O54839
707
74783
Y352
N
M
Q
G
N
K
M
Y
V
H
P
E
S
P
N
Rat
Rattus norvegicus
XP_001061749
663
70857
K329
R
Q
E
I
S
F
G
K
L
K
L
T
N
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514679
386
42515
N53
V
E
G
N
T
P
G
N
R
L
Y
V
H
P
D
Chicken
Gallus gallus
XP_426003
399
44936
H66
Q
G
N
K
V
Y
V
H
P
E
S
P
N
T
G
Frog
Xenopus laevis
P79944
692
75925
Y337
N
M
Q
G
N
K
V
Y
V
H
P
E
S
P
N
Zebra Danio
Brachydanio rerio
NP_571754
661
71990
T328
K
G
A
N
N
N
N
T
Q
M
I
V
L
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
Y410
P
E
M
P
K
R
M
Y
I
H
P
D
S
P
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
R88
M
V
I
T
K
S
G
R
R
I
F
P
A
Y
R
Sea Urchin
Strong. purpuratus
XP_791266
946
105128
Y451
I
P
K
V
S
N
I
Y
L
H
P
D
S
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
80
96.5
N.A.
87.5
81.6
N.A.
25.6
52.4
62.1
57.5
N.A.
22.9
N.A.
24.7
23.6
Protein Similarity:
100
99.1
82.9
96.9
N.A.
89.3
83.9
N.A.
33.5
54.5
70.5
68.9
N.A.
35.2
N.A.
34.9
37.9
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
6.6
0
93.3
6.6
N.A.
40
N.A.
0
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
13.3
20
100
13.3
N.A.
60
N.A.
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
8
% D
% Glu:
0
16
8
0
0
0
0
0
0
8
0
47
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
16
8
47
0
0
24
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
62
0
0
8
0
0
% H
% Ile:
8
0
8
8
0
0
8
0
8
8
8
0
0
0
0
% I
% Lys:
8
0
8
8
16
47
0
8
0
8
0
0
0
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
16
8
8
0
8
0
0
% L
% Met:
8
47
8
0
0
0
47
0
0
8
0
0
0
0
0
% M
% Asn:
47
0
8
16
54
16
8
8
0
0
0
0
16
8
47
% N
% Pro:
8
8
0
8
0
8
0
0
8
0
62
16
0
70
0
% P
% Gln:
8
8
47
0
0
0
0
0
8
0
0
0
0
8
0
% Q
% Arg:
8
0
0
0
0
8
0
8
16
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
16
8
0
0
0
0
8
0
62
0
16
% S
% Thr:
0
0
0
8
8
0
0
8
0
0
0
8
0
8
8
% T
% Val:
8
8
0
8
8
0
16
0
47
0
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
62
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _